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Interstate 40 is partially closed near Holbrook after authorities say a crash left four people dead Friday afternoon.Details surrounding the crash are limited, but the Arizona Department of Public Safety says multiple vehicles were involved and that the collision happened around 1:45 p.m. at milepost 294.Treacherous winter weather has led to a number of crashes across northern Arizona, including in Williams, where at least two people were killed in a fiery wreck on Thursday.Traffic officials have closed several interstates and highways across the state due to icy road conditions caused by this week’s winter storms.